Frederic BARD

Adjunct Associate Professor

+65 6478 9585
fbard@imcb.a-star.edu.sg

Affiliations

Adjunct Associate Professor, Department of Biochemistry, Yong Loo Lin School of Medicine, NUS.
Principal Investigator, Institute of Molecular & Cell Biology, A*STAR.

Research Interest

* Molecular mechanisms of protein secretion and Golgi apparatus organization.
* Biogenesis of mucin secretory granules.
* Genome-wide RNAi screening & High Content Screening.

Selected Publications

  1. Bard F and Malhotra V (2006) Transit from the Trans-Golgi Network to the plasma membrane. Annu Rev Cell Dev Biol. 22: 439-455.

  2. Bard F, Casano L, Mallabiabarrena A, Wallace E, Saito K, Kitayama H, Guizzinti G, Hu Y, DasGupta R, Perrimon N andMalhotra V (2006). Functional genomics reveals new genes involved in protein secretion and Golgi organization. Nature. 439(7076): 604-607.

  3. Yeaman C, Ayala MI, Wright JR, Bard F, Bossard C, Ang A, Maeda Y, Seufferlein T, Mellman I, Nelson WJ andMalhotra V (2004). Protein kinase D regulates basolateral membrane protein exit from trans-Golgi network. Nat Cell Biol. 6(2): 106-112.

  4. Saltel F, Destaing O, Bard F, Eichert D and Jurdic P (2004). Apatite-mediated actin dynamics in resorbing osteoclasts. Mol Biol Cell. 15: 5231-5241.

  5. Bard F, Mazelin L, Pechoux-Longin C, Malhotra V and Jurdic P (2003). Src regulates Golgi structure and KDEL receptor-dependent retrograde transport to the endoplasmic reticulum. J Biol Chem. 278(47): 46601-46606.

  6. Destaing O, Saltel F, Geminard JC, Jurdic P and Bard F (2003). Podosomes display actin turnover and dynamic self-organization in osteoclasts expressing actin-green fluorescent protein. Mol Biol Cell. 14(2): 407-416.